6JHS

The cryo-EM structure of HAV bound to a neutralizing antibody-F7

Summary for 6JHS

• Entry DOI: 10.2210/pdb6jhs/pdb
• EMDB information: 9829
• Descriptor: VP1, VP2, VP3, ... (5 entities in total)
• Functional Keywords: icosahedral symmetry, neutralizing antibody, hav, complex, virus
• Biological source: Human hepatitis A virus Hu/Australia/HM175/1976; More
• Total number of polymer chains: 5
• Total formula weight: 130789.05

Authors

Cao, L.,Liu, P.,Yang, P.,Gao, Q.,Li, H.,Sun, Y.,Zhu, L.,Lin, J.,Su, D.,Rao, Z.,Wang, X. (deposition date: 2019-02-19, release date: 2020-03-18)

• Primary citation: Cao, L.,Liu, P.,Yang, P.,Gao, Q.,Li, H.,Sun, Y.,Zhu, L.,Lin, J.,Su, D.,Rao, Z.,Wang, X.; Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors.; Plos Biol., 17:e3000229-e3000229, 2019; PubMed: 31039149; DOI: 10.1371/journal.pbio.3000229

Experimental method

ELECTRON MICROSCOPY (3.05 Å)