6JAW

Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with a napthalimide derivative

Summary for 6JAW

• Entry DOI: 10.2210/pdb6jaw/pdb
• Related: 5Y29
• Descriptor: Group II chitinase, 2-[3-(morpholin-4-yl)propyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: inhibitor complex, chitinase, hydrolase
• Biological source: Ostrinia furnacalis (Asian corn borer)
• Total number of polymer chains: 1
• Total formula weight: 45013.98

Authors

Chen, W.,Zhou, Y.,Yang, Q. (deposition date: 2019-01-25, release date: 2019-05-15, Last modification date: 2023-11-22)

• Primary citation: Chen, W.,Zhou, Y.,Yang, Q.; Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition.; J.Biol.Chem., 294:9358-9364, 2019; PubMed: 31053640; DOI: 10.1074/jbc.RA119.007812

Experimental method

X-RAY DIFFRACTION (1.981 Å)