6JAV

Crystal structure of Ostrinia furnacalis Group II chitinase catalytic domain 1 in complex with a piperidine-thienopyridine derivative

6JAV の概要

• エントリーDOI: 10.2210/pdb6jav/pdb
• 分子名称: Group II chitinase, 2-{[(4-chlorophenyl)methyl]sulfanyl}-7-methyl-N-(prop-2-en-1-yl)-7,8-dihydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: inhibitor complex, chitinase, hydrolase
• 由来する生物種: Ostrinia furnacalis (Asian corn borer)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45104.58

構造登録者

Chen, W.,Zhou, Y.,Yang, Q. (登録日: 2019-01-25, 公開日: 2019-05-15, 最終更新日: 2023-11-22)

• 主引用文献: Chen, W.,Zhou, Y.,Yang, Q.; Structural dissection reveals a general mechanistic principle for group II chitinase (ChtII) inhibition.; J.Biol.Chem., 294:9358-9364, 2019; PubMed: 31053640; DOI: 10.1074/jbc.RA119.007812

実験手法

X-RAY DIFFRACTION (1.437 Å)