6J8Y

Crystal structure of the human RAD9-HUS1-RAD1-RHINO complex

6J8Y の概要

• エントリーDOI: 10.2210/pdb6j8y/pdb
• 分子名称: Cell cycle checkpoint control protein RAD9A, Checkpoint protein HUS1, Cell cycle checkpoint protein RAD1, ... (5 entities in total)
• 機能のキーワード: dna damage, checkpoint, dna repair, dna binding clamp, cell cycle, exonuclease, hydrolase, nuclease, nucleus, phosphoprotein, pcna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 96367.69

構造登録者

Hara, K.,Iida, N.,Sakurai, H.,Hashimoto, H. (登録日: 2019-01-21, 公開日: 2019-12-04, 最終更新日: 2023-11-22)

• 主引用文献: Hara, K.,Iida, N.,Tamafune, R.,Ohashi, E.,Sakurai, H.,Ishikawa, Y.,Hishiki, A.,Hashimoto, H.; Structure of the RAD9-RAD1-HUS1 checkpoint clamp bound to RHINO sheds light on the other side of the DNA clamp.; J.Biol.Chem., 295:899-904, 2020; PubMed: 31776186; DOI: 10.1074/jbc.AC119.011816

実験手法

X-RAY DIFFRACTION (2.4 Å)