Summary for 6J5L
| Descriptor | High affinity nerve growth factor receptor, N-{2-[({3-[6-(piperazin-1-yl)pyridin-3-yl]-1H-indazol-5-yl}amino)methyl]phenyl}methanesulfonamide (3 entities in total) |
|---|---|
| Functional Keywords | transferase inhibitor, transferase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total molecular weight | 34739.2 |
| Authors | Kensuke, A.,Kazutaka, I. (deposition date: 2019-01-11, release date: 2019-07-17, Last modification date: 2019-07-24) |
| Primary citation | Shirahashi, H.,Toriihara, E.,Suenaga, Y.,Yoshida, H.,Akaogi, K.,Endou, Y.,Wakabayashi, M.,Takashima, M. The discovery of novel 3-aryl-indazole derivatives as peripherally restricted pan-Trk inhibitors for the treatment of pain. Bioorg.Med.Chem.Lett., 2019 PubMed: 31235262 (PDB entries with the same primary citation) DOI: 10.1016/j.bmcl.2019.06.018  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (2.3 Å) |
