6J39

Crystal structure of CmiS2 with inhibitor

Summary for 6J39

• Entry DOI: 10.2210/pdb6j39/pdb
• Descriptor: FAD-dependent glycine oxydase, FLAVIN-ADENINE DINUCLEOTIDE, (3R)-3-[(carboxymethyl)sulfanyl]nonanoic acid, ... (4 entities in total)
• Functional Keywords: flavoenzyme, polyketide biosynthesis, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• Biological source: Streptomyces sp. MJ635-86F5
• Total number of polymer chains: 2
• Total formula weight: 84591.82

Authors

Kawasaki, D.,Chisuga, T.,Miyanaga, A.,Kudo, F.,Eguchi, T. (deposition date: 2019-01-04, release date: 2019-06-12, Last modification date: 2023-11-22)

• Primary citation: Kawasaki, D.,Chisuga, T.,Miyanaga, A.,Kudo, F.,Eguchi, T.; Structural Analysis of the Glycine Oxidase Homologue CmiS2 Reveals a Unique Substrate Recognition Mechanism for Formation of a beta-Amino Acid Starter Unit in Cremimycin Biosynthesis.; Biochemistry, 58:2706-2709, 2019; PubMed: 31154757; DOI: 10.1021/acs.biochem.9b00444

Experimental method

X-RAY DIFFRACTION (2.45 Å)