6J0I
Structure of [Co2+-(Chromomycin A3)2]-d(TTGGCGAA)2 complex
Summary for 6J0I
Entry DOI | 10.2210/pdb6j0i/pdb |
Descriptor | DNA (5'-D(*TP*TP*GP*GP*CP*GP*AP*A)-3'), 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-(2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol, ... (6 entities in total) |
Functional Keywords | mismatch dna, chromomycin a3, drug-dna complex, g:g mismatch, dna-antibiotic complex, dna/antibiotic |
Biological source | synthetic construct |
Total number of polymer chains | 6 |
Total formula weight | 22048.06 |
Authors | Satange, R.B.,Chuang, C.Y.,Hou, M.H. (deposition date: 2018-12-24, release date: 2019-07-24, Last modification date: 2023-11-22) |
Primary citation | Satange, R.,Chuang, C.Y.,Neidle, S.,Hou, M.H. Polymorphic G:G mismatches act as hotspots for inducing right-handed Z DNA by DNA intercalation. Nucleic Acids Res., 47:8899-8912, 2019 Cited by PubMed: 31361900DOI: 10.1093/nar/gkz653 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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