6J04
Crystal structure of full length human LC3B delta G120 mutant (2_125)
Summary for 6J04
| Entry DOI | 10.2210/pdb6j04/pdb |
| Descriptor | Microtubule-associated proteins 1A/1B light chain 3B, SULFATE ION (3 entities in total) |
| Functional Keywords | lc3b, microtubule-associated protein light chain-3, autophage, protein binding |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 4 |
| Total formula weight | 58507.45 |
| Authors | Ding, Y.,Lu, B.X.,Wang, Z.Y. (deposition date: 2018-12-21, release date: 2019-11-06, Last modification date: 2023-11-22) |
| Primary citation | Li, Z.Y.,Wang, C.,Wang, Z.Y.,Zhu, C.G.,Li, J.,Sha, T.,Ma, L.X.,Gao, C.,Yang, Y.,Sun, Y.M.,Wang, J.,Sun, X.L.,Lu, C.Q.,Difiglia, M.,Mein, Y.,Ding, C.,Luo, S.Q.,Dang, Y.J.,Ding, Y.,Fei, Y.Y.,Lu, B.X. Allele-selective lowering of mutant HTT protein by HTT-LC3 linker compounds Nature, 575:203-209, 2019 Cited by PubMed: 31666698DOI: 10.1038/s41586-019-1722-1 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.899 Å) |
Structure validation
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