6ITV

Crystal structure of activated c-KIT in complex with compound

Summary for 6ITV

• Entry DOI: 10.2210/pdb6itv/pdb
• Descriptor: Mast/stem cell growth factor receptor Kit, N-(5-ethyl-1,2-oxazol-3-yl)-N'-[4-(2-{[6-(4-ethylpyrazin-1(4H)-yl)pyrimidin-4-yl]amino}-1,3-thiazol-5-yl)phenyl]urea (3 entities in total)
• Functional Keywords: receptor tyrosine kinase dfg motif conformational control inhibitor, oncoprotein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 38265.13

Authors

Wu, T.S.,Wu, S.Y. (deposition date: 2018-11-26, release date: 2019-11-27, Last modification date: 2024-11-13)

• Primary citation: Wu, T.S.,Wu, S.Y.; Crystal structure of activated c-KIT in complex with compound; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.881 Å)