6ITV

Crystal structure of activated c-KIT in complex with compound

6ITV の概要

• エントリーDOI: 10.2210/pdb6itv/pdb
• 分子名称: Mast/stem cell growth factor receptor Kit, N-(5-ethyl-1,2-oxazol-3-yl)-N'-[4-(2-{[6-(4-ethylpyrazin-1(4H)-yl)pyrimidin-4-yl]amino}-1,3-thiazol-5-yl)phenyl]urea (3 entities in total)
• 機能のキーワード: receptor tyrosine kinase dfg motif conformational control inhibitor, oncoprotein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 38265.13

構造登録者

Wu, T.S.,Wu, S.Y. (登録日: 2018-11-26, 公開日: 2019-11-27, 最終更新日: 2024-11-13)

• 主引用文献: Wu, T.S.,Wu, S.Y.; Crystal structure of activated c-KIT in complex with compound; To Be Published,

実験手法

X-RAY DIFFRACTION (1.881 Å)