6ITU
Crystal Structure of the GULP1 PTB domain-APP peptide complex
Summary for 6ITU
Entry DOI | 10.2210/pdb6itu/pdb |
Descriptor | PTB domain-containing engulfment adapter protein 1, Amyloid beta A4 protein, SULFATE ION, ... (5 entities in total) |
Functional Keywords | ptb, app-binding, phosphoprotein, cytoplasmic, protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 21198.25 |
Authors | Yung, K.W.Y.,Lau, K.F.,Ngo, J.C.K. (deposition date: 2018-11-26, release date: 2019-08-14, Last modification date: 2023-11-22) |
Primary citation | Chau, D.D.,Yung, K.W.,Chan, W.W.,An, Y.,Hao, Y.,Chan, H.E.,Ngo, J.C.,Lau, K.F. Attenuation of amyloid-beta generation by atypical protein kinase C-mediated phosphorylation of engulfment adaptor PTB domain containing 1 threonine 35. Faseb J., 33:12019-12035, 2019 Cited by PubMed: 31373844DOI: 10.1096/fj.201802825RR PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.17 Å) |
Structure validation
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