6IRS

human LAT1-4F2hc complex incubated with JPH203

Summary for 6IRS

• Entry DOI: 10.2210/pdb6irs/pdb
• EMDB information: 9721
• Descriptor: 4F2 cell-surface antigen heavy chain, Large neutral amino acids transporter small subunit 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: transporter, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 130513.36

Authors

Yan, R.H.,Zhao, X.,Lei, J.L.,Zhou, Q. (deposition date: 2018-11-14, release date: 2019-03-27, Last modification date: 2020-07-29)

• Primary citation: Yan, R.,Zhao, X.,Lei, J.,Zhou, Q.; Structure of the human LAT1-4F2hc heteromeric amino acid transporter complex.; Nature, 568:127-130, 2019; PubMed: 30867591; DOI: 10.1038/s41586-019-1011-z

Experimental method

ELECTRON MICROSCOPY (3.3 Å)