6IPK

Binary Complex of Human DNA Polymerase Mu with Mn8oxodGTP

Summary for 6IPK

Entry DOI	10.2210/pdb6ipk/pdb
Descriptor	DNA-directed DNA/RNA polymerase mu, MANGANESE (II) ION, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywords	dna polymerase mu, dna break repair, transferase-dntp complex, 8-oxo-dgtp, transferase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	1
Total formula weight	41502.17
Authors	Chang, Y.K.,Wu, W.J.,Tsai, M.D. (deposition date: 2018-11-03, release date: 2019-05-29, Last modification date: 2024-03-27)
Primary citation	Chang, Y.K.,Huang, Y.P.,Liu, X.X.,Ko, T.P.,Bessho, Y.,Kawano, Y.,Maestre-Reyna, M.,Wu, W.J.,Tsai, M.D. Human DNA Polymerase mu Can Use a Noncanonical Mechanism for Multiple Mn2+-Mediated Functions. J.Am.Chem.Soc., 141:8489-8502, 2019 Cited by PubMed: 31067051 DOI: 10.1021/jacs.9b01741 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation