6IAA

hRobo2 ectodomain

6IAA の概要

• エントリーDOI: 10.2210/pdb6iaa/pdb
• 関連するPDBエントリー: 6I9S
• 分子名称: Roundabout homolog 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• 機能のキーワード: slit, robo, axon guidance, cell surface receptor, signaling protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 291925.37

構造登録者

Barak, R.,Isupov, N.M.,Opatowsky, Y. (登録日: 2018-11-26, 公開日: 2019-03-13, 最終更新日: 2020-07-29)

• 主引用文献: Barak, R.,Yom-Tov, G.,Guez-Haddad, J.,Gasri-Plotnitsky, L.,Maimon, R.,Cohen-Berkman, M.,McCarthy, A.A.,Perlson, E.,Henis-Korenblit, S.,Isupov, M.N.,Opatowsky, Y.; Structural Principles in Robo Activation and Auto-inhibition.; Cell, 177:272-285.e16, 2019; PubMed: 30853216; DOI: 10.1016/j.cell.2019.02.004

実験手法

X-RAY DIFFRACTION (3.6 Å)