6I1E

Crystal structure of Pseudomonas aeruginosa Penicillin-Binding Protein 3 in complex with amoxicillin

Summary for 6I1E

Entry DOI	10.2210/pdb6i1e/pdb
Related	6HZH 6HZI 6HZJ 6HZO 6HZQ 6HZR
Descriptor	Peptidoglycan D,D-transpeptidase FtsI, 2-{1-[2-AMINO-2-(4-HYDROXY-PHENYL)-ACETYLAMINO]-2-OXO-ETHYL}-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID (3 entities in total)
Functional Keywords	penicillin-binding protein, peptidoglycan, transpeptidase, peptide binding protein
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	1
Total formula weight	58394.47
Authors	Bellini, D.,Dowson, C.G. (deposition date: 2018-10-28, release date: 2019-11-20, Last modification date: 2024-01-24)
Primary citation	Bellini, D.,Koekemoer, L.,Newman, H.,Dowson, C.G. Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of beta-Lactam Target-Mediated Resistance. J.Mol.Biol., 431:3501-3519, 2019 Cited by PubMed: 31301409 DOI: 10.1016/j.jmb.2019.07.010 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.64 Å)

Structure validation