6HMY
Cholera toxin classical B-pentamer in complex with fucosyl-GM1
Summary for 6HMY
Entry DOI | 10.2210/pdb6hmy/pdb |
Related | 5ELB 6HJD 6HMW |
Descriptor | Cholera enterotoxin B-subunit, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-beta-D-glucopyranose, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose-(1-4)-[N-acetyl-alpha-neuraminic acid-(2-3)]beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, ... (8 entities in total) |
Functional Keywords | toxin, cholera toxin, lectin, complex, fucosyl-gm1, protein-carbohydrate interactions, x-ray crystal structure |
Biological source | Vibrio cholerae |
Total number of polymer chains | 10 |
Total formula weight | 130043.74 |
Authors | Krengel, U.,Heim, J.B. (deposition date: 2018-09-13, release date: 2019-08-14, Last modification date: 2024-01-24) |
Primary citation | Heim, J.B.,Hodnik, V.,Heggelund, J.E.,Anderluh, G.,Krengel, U. Crystal structures of cholera toxin in complex with fucosylated receptors point to importance of secondary binding site. Sci Rep, 9:12243-12243, 2019 Cited by PubMed: 31439922DOI: 10.1038/s41598-019-48579-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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