6HK2

Crystal structure of ferric R-state human methemoglobin bound to maleimide-deferoxamine bifunctional chelator (DFO)

6HK2 の概要

• エントリーDOI: 10.2210/pdb6hk2/pdb
• 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... (7 entities in total)
• 機能のキーワード: oxygen transport, dfo, complex, beta cys93
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 65619.87

構造登録者

Cerutti, G.,Savino, C.,Montemiglio, L.C.,Boffi, A. (登録日: 2018-09-05, 公開日: 2019-09-18, 最終更新日: 2024-01-17)

• 主引用文献: Kiraga, L.,Cerutti, G.,Braniewska, A.,Strzemecki, D.,Sas, Z.,Boffi, A.,Savino, C.,Montemiglio, L.C.,Turnham, D.,Seaton, G.,Bonamore, A.,Clarkson, R.,Dabkowski, A.M.,Paisey, S.J.,Taciak, B.,Kucharzewska, P.,Rygiel, T.P.,Krol, M.; Biodistribution PET/CT Study of Hemoglobin-DFO-89Zr Complex in Healthy and Lung Tumor-Bearing Mice.; Int J Mol Sci, 21:-, 2020; PubMed: 32679799; DOI: 10.3390/ijms21144991

実験手法

X-RAY DIFFRACTION (1.55 Å)