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6HI3

The ATAD2 bromodomain in complex with compound 4

Summary for 6HI3
Entry DOI10.2210/pdb6hi3/pdb
DescriptorATPase family AAA domain-containing protein 2, 2-azanyl-~{N}-(4-ethanoyl-1,3-thiazol-2-yl)-2-methyl-propanamide, SULFATE ION, ... (4 entities in total)
Functional Keywordsbromodomain, atad2, inhibitor, complex, cytosolic protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight15776.86
Authors
Sledz, P.,Caflisch, A. (deposition date: 2018-08-29, release date: 2019-02-20, Last modification date: 2024-01-17)
Primary citationDolbois, A.,Batiste, L.,Wiedmer, L.,Dong, J.,Brutsch, M.,Huang, D.,Deerain, N.M.,Spiliotopoulos, D.,Cheng-Sanchez, I.,Laul, E.,Nevado, C.,Sledz, P.,Caflisch, A.
Hitting a Moving Target: Simulation and Crystallography Study of ATAD2 Bromodomain Blockers.
Acs Med.Chem.Lett., 11:1573-1580, 2020
Cited by
PubMed: 32832026
DOI: 10.1021/acsmedchemlett.0c00080
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

217705

數據於2024-03-27公開中

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