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6HFR

Human dihydroorotase mutant F1563Y co-crystallized with carbamoyl aspartate at pH 7.0

Summary for 6HFR
Entry DOI10.2210/pdb6hfr/pdb
DescriptorCAD protein, ZINC ION, N-CARBAMOYL-L-ASPARTATE, ... (5 entities in total)
Functional Keywordsde novo pyrimidine biosynthesis, cad, tim-barrel, carboxylated lysine, biosynthetic protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight43493.83
Authors
Ramon-Maiques, S.,Grande Garcia, A. (deposition date: 2018-08-21, release date: 2018-10-24, Last modification date: 2024-01-17)
Primary citationDel Cano-Ochoa, F.,Grande-Garcia, A.,Reverte-Lopez, M.,D'Abramo, M.,Ramon-Maiques, S.
Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.
J. Biol. Chem., 293:18903-18913, 2018
Cited by
PubMed: 30315107
DOI: 10.1074/jbc.RA118.005494
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.29949373933 Å)
Structure validation

217705

数据于2024-03-27公开中

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