6HFJ
Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.5
Summary for 6HFJ
Entry DOI | 10.2210/pdb6hfj/pdb |
Descriptor | CAD protein, ZINC ION, FORMIC ACID, ... (5 entities in total) |
Functional Keywords | de novo pyrimidine biosynthesis, cad, tim-barrel, carboxylated lysine, biosynthetic protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 43397.74 |
Authors | Ramon-Maiques, S.,Grande Garcia, A. (deposition date: 2018-08-21, release date: 2018-10-24, Last modification date: 2024-01-17) |
Primary citation | Del Cano-Ochoa, F.,Grande-Garcia, A.,Reverte-Lopez, M.,D'Abramo, M.,Ramon-Maiques, S. Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD. J. Biol. Chem., 293:18903-18913, 2018 Cited by PubMed: 30315107DOI: 10.1074/jbc.RA118.005494 PDB entries with the same primary citation |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)