6HEB

Influenza A Virus N9 Neuraminidase complex with Oseltamivir (Tern).

Summary for 6HEB

• Entry DOI: 10.2210/pdb6heb/pdb
• Descriptor: Neuraminidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: complex, oseltamivir, tamiflu, neuraminidase, n9, influenza, virus, hydrolase, enzyme, inhibitor, gs4071
• Biological source: Influenza A virus (strain A/Tern/Australia/G70C/1975 H11N9)
• Total number of polymer chains: 1
• Total formula weight: 47049.03

Authors

Salinger, M.T.,Hobbs, J.R.,Murray, J.W.,Laver, W.G.,Kuhn, P.,Garman, E.F. (deposition date: 2018-08-20, release date: 2018-08-29, Last modification date: 2024-01-17)

• Primary citation: Salinger, M.T.,Hobbs, J.R.,Murray, J.W.,Laver, W.G.,Kuhn, P.,Garman, E.F.; High Resolution Structures of Viral Neuraminidase with Drugs Bound in the Active Site.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.75 Å)