6H80
Dengue-RdRp3-inhibitor complex co-crystallisation
Summary for 6H80
Entry DOI | 10.2210/pdb6h80/pdb |
Descriptor | Genome polyprotein, 2-(4-methoxy-3-thiophen-2-yl-phenyl)ethanoic acid, ZINC ION, ... (5 entities in total) |
Functional Keywords | dengue virus; crystallization screen; rna-dependent rna polymerase; flavivirus; antiviral drug-discovery, viral protein |
Biological source | Dengue virus type 3 (strain Sri Lanka/1266/2000) (DENV-3) |
Total number of polymer chains | 1 |
Total formula weight | 74534.58 |
Authors | Talapatra, S.K.,Kozielski, F. (deposition date: 2018-07-31, release date: 2019-03-13, Last modification date: 2024-01-17) |
Primary citation | Riccio, F.,Talapatra, S.K.,Oxenford, S.,Angell, R.,Mazzon, M.,Kozielski, F. Development and validation of RdRp Screen, a crystallization screen for viral RNA-dependent RNA polymerases. Biol Open, 8:-, 2019 Cited by PubMed: 30602529DOI: 10.1242/bio.037663 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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