6H59

Crystal structure of Mycobacterium tuberculosis phosphatidylinositol phosphate synthase (PgsA1) with CDP-DAG bound

Summary for 6H59

Entry DOI	10.2210/pdb6h59/pdb
Related	6H53
Descriptor	CDP-diacylglycerol--inositol 3-phosphatidyltransferase, MAGNESIUM ION, SULFATE ION, ... (8 entities in total)
Functional Keywords	phosphotransferase, glycerophospholipid metabolism, metal binding protein, membrane protein, transferase
Biological source	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Total number of polymer chains	2
Total formula weight	54337.98
Authors	Grave, K.,Hogbom, M. (deposition date: 2018-07-24, release date: 2019-05-15, Last modification date: 2024-01-17)
Primary citation	Grave, K.,Bennett, M.D.,Hogbom, M. Structure ofMycobacterium tuberculosisphosphatidylinositol phosphate synthase reveals mechanism of substrate binding and metal catalysis. Commun Biol, 2:175-175, 2019 Cited by PubMed: 31098408 DOI: 10.1038/s42003-019-0427-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation