6H3M
The crystal structure of a human seleno-insulin analog
Summary for 6H3M
| Entry DOI | 10.2210/pdb6h3m/pdb |
| Descriptor | Insulin (3 entities in total) |
| Functional Keywords | insulin, selenocysteine, analog, human, hormone |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 16 |
| Total formula weight | 47291.53 |
| Authors | Lansky, S.,Weil-Ktorza, O.,Metanis, N.,Shoham, G. (deposition date: 2018-07-19, release date: 2019-08-14, Last modification date: 2020-08-26) |
| Primary citation | Weil-Ktorza, O.,Rege, N.,Lansky, S.,Shalev, D.E.,Shoham, G.,Weiss, M.A.,Metanis, N. Substitution of an Internal Disulfide Bridge with a Diselenide Enhances both Foldability and Stability of Human Insulin. Chemistry, 25:8513-8521, 2019 Cited by PubMed: 31012517DOI: 10.1002/chem.201900892 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.821 Å) |
Structure validation
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