6H3E
Receptor-bound Ghrelin conformation
Summary for 6H3E
Entry DOI | 10.2210/pdb6h3e/pdb |
NMR Information | BMRB: 34303 |
Descriptor | Appetite-regulating hormone, octan-1-amine (2 entities in total) |
Functional Keywords | neuropeptide, acyl chain, growth hormone secretagogue receptor, gpcr, lipopeptide hormone, obesity, diabetes, addiction., hormone |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 2259.54 |
Authors | Ferre, G.,Damian, M.,M'Kadmi, C.,Saurel, O.,Czaplicki, G.,Demange, P.,Marie, J.,Fehrentz, J.A.,Baneres, J.L.,Milon, A. (deposition date: 2018-07-18, release date: 2019-07-24, Last modification date: 2023-06-14) |
Primary citation | Ferre, G.,Louet, M.,Saurel, O.,Delort, B.,Czaplicki, G.,M'Kadmi, C.,Damian, M.,Renault, P.,Cantel, S.,Gavara, L.,Demange, P.,Marie, J.,Fehrentz, J.A.,Floquet, N.,Milon, A.,Baneres, J.L. Structure and dynamics of G protein-coupled receptor-bound ghrelin reveal the critical role of the octanoyl chain. Proc.Natl.Acad.Sci.USA, 116:17525-17530, 2019 Cited by PubMed: 31416915DOI: 10.1073/pnas.1905105116 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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