6H2C
Structure of BlaC from Mycobacterium tuberculosis bound to the trans-enamine adduct derived from clavulanic acid.
Summary for 6H2C
Entry DOI | 10.2210/pdb6h2c/pdb |
Descriptor | Beta-lactamase, (2E)-3-[(4-hydroxy-2-oxobutyl)amino]prop-2-enal, ACETATE ION, ... (7 entities in total) |
Functional Keywords | hydrolase |
Biological source | Mycobacterium tuberculosis |
Total number of polymer chains | 2 |
Total formula weight | 62696.39 |
Authors | Tassoni, R.,Pannu, N.S.,Ubbink, M. (deposition date: 2018-07-13, release date: 2019-01-23, Last modification date: 2024-01-17) |
Primary citation | Tassoni, R.,Blok, A.,Pannu, N.S.,Ubbink, M. New Conformations of Acylation Adducts of Inhibitors of beta-Lactamase from Mycobacterium tuberculosis. Biochemistry, 58:997-1009, 2019 Cited by PubMed: 30632739DOI: 10.1021/acs.biochem.8b01085 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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