6H1Y

CRYSTAL STRUCTURE OF A CHIMERIC VARIANT OF THIOREDOXIN FROM ESCHERICHIA COLI

Summary for 6H1Y

Entry DOI	10.2210/pdb6h1y/pdb
Descriptor	Thioredoxin 1,Thioredoxin (TrxA-1),Thioredoxin 1 (1 entity in total)
Functional Keywords	protein thermal stability, loop size optimization, fundamental rules, chimeric proteins, protein stabilization, oxidoreductase
Biological source	Escherichia coli More
Total number of polymer chains	2
Total formula weight	23569.14
Authors	Ruggiero, A.,Smaldone, G.,Esposito, L.,Balasco, N.,Vitagliano, L. (deposition date: 2018-07-12, release date: 2019-02-06, Last modification date: 2024-01-17)
Primary citation	Ruggiero, A.,Smaldone, G.,Esposito, L.,Balasco, N.,Vitagliano, L. Loop size optimization induces a strong thermal stabilization of the thioredoxin fold. Febs J., 286:1752-1764, 2019 Cited by PubMed: 30675750 DOI: 10.1111/febs.14767 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.99 Å)

Structure validation