6H1O

Structure of the BM3 heme domain in complex with voriconazole

6H1O の概要

• エントリーDOI: 10.2210/pdb6h1o/pdb
• 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, Voriconazole, ... (7 entities in total)
• 機能のキーワード: p450, azole inhibitor, heme ligation, p450 bm3, oxidoreductase
• 由来する生物種: Bacillus megaterium
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 107460.13

構造登録者

Jeffreys, L.N.,Munro, A.W.M.,Leys, D. (登録日: 2018-07-12, 公開日: 2019-02-20, 最終更新日: 2024-01-17)

• 主引用文献: Jeffreys, L.N.,Poddar, H.,Golovanova, M.,Levy, C.W.,Girvan, H.M.,McLean, K.J.,Voice, M.W.,Leys, D.,Munro, A.W.; Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs.; Sci Rep, 9:1577-1577, 2019; PubMed: 30733479; DOI: 10.1038/s41598-018-37330-y

実験手法

X-RAY DIFFRACTION (1.734 Å)