6GZ9

Crystal structure of a POT family transporter in complex with prodrug valacyclovir

Summary for 6GZ9

Entry DOI	10.2210/pdb6gz9/pdb
Descriptor	Peptide ABC transporter permease, 2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate (3 entities in total)
Functional Keywords	peptide transporter; prodrug complex, membrane protein
Biological source	Staphylococcus hominis
Total number of polymer chains	1
Total formula weight	54275.38
Authors	Minhas, G.S.,Newstead, S. (deposition date: 2018-07-03, release date: 2018-12-26, Last modification date: 2024-01-17)
Primary citation	Minhas, G.S.,Newstead, S. Structural basis for prodrug recognition by the SLC15 family of proton-coupled peptide transporters. Proc. Natl. Acad. Sci. U.S.A., 116:804-809, 2019 Cited by PubMed: 30602453 DOI: 10.1073/pnas.1813715116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation