6GX5
Narrow Pick Filament from Pick's disease brain
Summary for 6GX5
Entry DOI | 10.2210/pdb6gx5/pdb |
EMDB information | 0077 |
Descriptor | Microtubule-associated protein tau (1 entity in total) |
Functional Keywords | tau protein, tau, pick's disease, tauopathy, neurodegenerative disease, proteinopathy, amyloid, filament, helical, pick body, fibril, neurodegeneration, mapt, microtubule-associated protein tau, protein fibril |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 30407.00 |
Authors | Falcon, B.,Zhang, W.,Murzin, A.G.,Murshudov, G.,Garringer, H.J.,Vidal, R.,Crowther, R.A.,Ghetti, B.,Scheres, S.H.W.,Goedert, M. (deposition date: 2018-06-26, release date: 2018-09-12, Last modification date: 2024-07-10) |
Primary citation | Falcon, B.,Zhang, W.,Murzin, A.G.,Murshudov, G.,Garringer, H.J.,Vidal, R.,Crowther, R.A.,Ghetti, B.,Scheres, S.H.W.,Goedert, M. Structures of filaments from Pick's disease reveal a novel tau protein fold. Nature, 561:137-140, 2018 Cited by PubMed: 30158706DOI: 10.1038/s41586-018-0454-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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