6GV1

Crystal structure of E.coli Multidrug/H+ antiporter MdfA in outward open conformation with bound Fab fragment

Summary for 6GV1

Entry DOI	10.2210/pdb6gv1/pdb
Descriptor	Major Facilitator Superfamily multidrug/H+ antiporter MdfA from E.coli, Fab fragment YN1074 heavy chain, Fab fragment YN1074 light chain, ... (4 entities in total)
Functional Keywords	major facilitator superfamily, multidrug resistance, proton transport, mfs transporter, drug proton antiporter, transport protein
Biological source	Escherichia coli K-12 More
Total number of polymer chains	3
Total formula weight	93062.93
Authors	Nagarathinam, K.,Parthier, C.,Stubbs, M.T.,Tanabe, M. (deposition date: 2018-06-20, release date: 2018-10-03, Last modification date: 2024-01-17)
Primary citation	Nagarathinam, K.,Nakada-Nakura, Y.,Parthier, C.,Terada, T.,Juge, N.,Jaenecke, F.,Liu, K.,Hotta, Y.,Miyaji, T.,Omote, H.,Iwata, S.,Nomura, N.,Stubbs, M.T.,Tanabe, M. Outward open conformation of a Major Facilitator Superfamily multidrug/H+antiporter provides insights into switching mechanism. Nat Commun, 9:4005-4005, 2018 Cited by PubMed: 30275448 DOI: 10.1038/s41467-018-06306-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.4 Å)

Structure validation