6GV1

Crystal structure of E.coli Multidrug/H+ antiporter MdfA in outward open conformation with bound Fab fragment

6GV1 の概要

• エントリーDOI: 10.2210/pdb6gv1/pdb
• 分子名称: Major Facilitator Superfamily multidrug/H+ antiporter MdfA from E.coli, Fab fragment YN1074 heavy chain, Fab fragment YN1074 light chain, ... (4 entities in total)
• 機能のキーワード: major facilitator superfamily, multidrug resistance, proton transport, mfs transporter, drug proton antiporter, transport protein
• 由来する生物種: Escherichia coli K-12; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 93062.93

構造登録者

Nagarathinam, K.,Parthier, C.,Stubbs, M.T.,Tanabe, M. (登録日: 2018-06-20, 公開日: 2018-10-03, 最終更新日: 2024-01-17)

• 主引用文献: Nagarathinam, K.,Nakada-Nakura, Y.,Parthier, C.,Terada, T.,Juge, N.,Jaenecke, F.,Liu, K.,Hotta, Y.,Miyaji, T.,Omote, H.,Iwata, S.,Nomura, N.,Stubbs, M.T.,Tanabe, M.; Outward open conformation of a Major Facilitator Superfamily multidrug/H+antiporter provides insights into switching mechanism.; Nat Commun, 9:4005-4005, 2018; PubMed: 30275448; DOI: 10.1038/s41467-018-06306-x

実験手法

X-RAY DIFFRACTION (3.4 Å)