6GR3
Structure of human Heat shock protein 90-alpha N-terminal domain (Hsp90-NTD) variant K112R in complex with AMPPNP
Summary for 6GR3
Entry DOI | 10.2210/pdb6gr3/pdb |
Related | 6GP4 6GPW 6GQS 6GQU 6GR1 |
Descriptor | Heat shock protein HSP 90-alpha, AMP PHOSPHORAMIDATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | chaperone, hsp90, ntd, alpha, k112r, complex, nucleotide, amppnp |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 29251.68 |
Authors | Tassone, G.,Pozzi, C.,Mangani, S.,Botta, M. (deposition date: 2018-06-08, release date: 2018-10-03, Last modification date: 2024-01-17) |
Primary citation | Tassone, G.,Mangani, S.,Botta, M.,Pozzi, C. Probing the role of Arg97 in Heat shock protein 90 N-terminal domain from the parasite Leishmania braziliensis through site-directed mutagenesis on the human counterpart. Biochim Biophys Acta Proteins Proteom, 1866:1190-1198, 2018 Cited by PubMed: 30248409DOI: 10.1016/j.bbapap.2018.09.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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