6GQS

Structure of human Heat shock protein 90-alpha N-terminal domain (Hsp90-NTD) variant K112R in complex with AMPCP

6GQS の概要

• エントリーDOI: 10.2210/pdb6gqs/pdb
• 関連するPDBエントリー: 6GP4 6GPW
• 分子名称: Heat shock protein HSP 90-alpha, PHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MAGNESIUM ION, ... (4 entities in total)
• 機能のキーワード: chaperone, hsp90, ntd, alpha, k112r, complex, nucleotide, ampcp
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29274.99

構造登録者

Tassone, G.,Pozzi, C.,Mangani, S.,Botta, M. (登録日: 2018-06-08, 公開日: 2018-10-03, 最終更新日: 2024-01-17)

• 主引用文献: Tassone, G.,Mangani, S.,Botta, M.,Pozzi, C.; Probing the role of Arg97 in Heat shock protein 90 N-terminal domain from the parasite Leishmania braziliensis through site-directed mutagenesis on the human counterpart.; Biochim Biophys Acta Proteins Proteom, 1866:1190-1198, 2018; PubMed: 30248409; DOI: 10.1016/j.bbapap.2018.09.005

実験手法

X-RAY DIFFRACTION (1.43 Å)