6GQB

Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GDP+AlF4/sordarin)

This is a non-PDB format compatible entry.

Summary for 6GQB

• Entry DOI: 10.2210/pdb6gqb/pdb
• Related: 6GQ1 6GQV
• EMDB information: 0047 0048 0049 0055
• Descriptor: Saccharomyces cerevisiae S288C 35S pre-ribosomal RNA (RDN37-1), miscRNA, 60S ribosomal protein L6-A, 60S ribosomal protein L7-A, ... (88 entities in total)
• Functional Keywords: eukaryotic 80s ribosome, eef2, translation fidelity, diphthamide, ribosome
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 84
• Total formula weight: 3192520.80

Authors

Pellegrino, S.,Yusupov, M.,Yusupova, G.,Hashem, Y. (deposition date: 2018-06-07, release date: 2018-07-11, Last modification date: 2021-08-04)

• Primary citation: Pellegrino, S.,Demeshkina, N.,Mancera-Martinez, E.,Melnikov, S.,Simonetti, A.,Myasnikov, A.,Yusupov, M.,Yusupova, G.,Hashem, Y.; Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.; J. Mol. Biol., 430:2677-2687, 2018; PubMed: 29886014; DOI: 10.1016/j.jmb.2018.06.006

Experimental method

ELECTRON MICROSCOPY (3.9 Å)