6GQ1

Cryo-EM reconstruction of yeast 80S ribosome in complex with mRNA, tRNA and eEF2 (GMPPCP/sordarin)

This is a non-PDB format compatible entry.

Summary for 6GQ1

• Entry DOI: 10.2210/pdb6gq1/pdb
• Related: 6GQB 6GQV
• EMDB information: 0047 0048 0049
• Descriptor: Saccharomyces cerevisiae S288C 35S pre-ribosomal RNA (RDN37-1), miscRNA, 60S ribosomal protein L6-A, 60S ribosomal protein L7-A, ... (86 entities in total)
• Functional Keywords: eukaryotic 80s riboosme, mrna-trna translocation, diphthamide, ribosome
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); More
• Total number of polymer chains: 83
• Total formula weight: 3169726.86

Authors

Pellegrino, S.,Demeshkina, N.,Mancera-Martinez, E.,Melnikov, S.,Simonetti, A.,Myasnikov, A.,Yusupov, M.,Yusupova, G.,Hashem, Y. (deposition date: 2018-06-07, release date: 2018-07-11, Last modification date: 2018-08-08)

• Primary citation: Pellegrino, S.,Demeshkina, N.,Mancera-Martinez, E.,Melnikov, S.,Simonetti, A.,Myasnikov, A.,Yusupov, M.,Yusupova, G.,Hashem, Y.; Structural Insights into the Role of Diphthamide on Elongation Factor 2 in mRNA Reading-Frame Maintenance.; J. Mol. Biol., 430:2677-2687, 2018; PubMed: 29886014; DOI: 10.1016/j.jmb.2018.06.006

Experimental method

ELECTRON MICROSCOPY (4.4 Å)