6GKO
Mouse thymidylate synthase cocrystallized with dUMP and soaked in phenolphthalein
Summary for 6GKO
Entry DOI | 10.2210/pdb6gko/pdb |
Descriptor | Thymidylate synthase, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one, ... (5 entities in total) |
Functional Keywords | fragment screening, fragment, inhibitor, transferase |
Biological source | Mus musculus (Mouse) |
Total number of polymer chains | 2 |
Total formula weight | 71411.31 |
Authors | Maj, P.,Wilk, P.,Jarmula, A.,Weiss, M.S.,Rode, W. (deposition date: 2018-05-21, release date: 2019-06-05, Last modification date: 2024-01-17) |
Primary citation | Maj, P.,Wilk, P.,Jarmula, A.,Weiss, M.S.,Rode, W. Thymidylate synthase fragment screening To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.839 Å) |
Structure validation
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