6GKO

Mouse thymidylate synthase cocrystallized with dUMP and soaked in phenolphthalein

Summary for 6GKO

• Entry DOI: 10.2210/pdb6gko/pdb
• Descriptor: Thymidylate synthase, 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one, ... (5 entities in total)
• Functional Keywords: fragment screening, fragment, inhibitor, transferase
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 2
• Total formula weight: 71411.31

Authors

Maj, P.,Wilk, P.,Jarmula, A.,Weiss, M.S.,Rode, W. (deposition date: 2018-05-21, release date: 2019-06-05, Last modification date: 2024-01-17)

• Primary citation: Maj, P.,Wilk, P.,Jarmula, A.,Weiss, M.S.,Rode, W.; Thymidylate synthase fragment screening; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.839 Å)