6GH1

HLA-E*01:03 in complex with Mtb44

Summary for 6GH1

DescriptorMHC class I antigen, Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], ... (6 entities in total)
Functional Keywordscomplex, histocompatibility antigen, immune system
Biological sourceHomo sapiens (Human)
More
Total number of polymer chains12
Total molecular weight179047.43
Authors
Walters, L.C.,Gillespie, G.M.,McMichael, A.J.,Rozbesky, D.,Jones, E.Y.,Harlos, K. (deposition date: 2018-05-04, release date: 2018-08-08, Last modification date: 2018-08-22)
Primary citation
Walters, L.C.,Harlos, K.,Brackenridge, S.,Rozbesky, D.,Barrett, J.R.,Jain, V.,Walter, T.S.,O'Callaghan, C.A.,Borrow, P.,Toebes, M.,Hansen, S.G.,Sacha, J.,Abdulhaqq, S.,Greene, J.M.,Fruh, K.,Marshall, E.,Picker, L.J.,Jones, E.Y.,McMichael, A.J.,Gillespie, G.M.
Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Nat Commun, 9:3137-3137, 2018
PubMed: 30087334 (PDB entries with the same primary citation)
DOI: 10.1038/s41467-018-05459-z
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.229400.5%1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution