6G9W

Crystal Structure of Aspergillus fumigatus UDP-N-acetylglucosamine pyrophosphorylase in complex with UTP

6G9W の概要

• エントリーDOI: 10.2210/pdb6g9w/pdb
• 分子名称: UDP-N-acetylglucosamine pyrophosphorylase, URIDINE 5'-TRIPHOSPHATE (3 entities in total)
• 機能のキーワード: aspergillus fumigatus, pyrophosphorylase, catalysis, cell wall, anti fungal, transferase
• 由来する生物種: Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 114555.46

構造登録者

Raimi, O.G.,Hurtado-Guerrero, R.,Borodin, V.,Urbaniak, M.,Ferguson, M.,van Aalten, D. (登録日: 2018-04-11, 公開日: 2019-04-24, 最終更新日: 2024-01-17)

• 主引用文献: Raimi, O.G.,Hurtado-Guerrero, R.,Borodkin, V.,Ferenbach, A.,Urbaniak, M.D.,Ferguson, M.A.J.,van Aalten, D.M.F.; A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor; RSC Chem. Biol., 2020; DOI: 10.1039/C9CB00017H

実験手法

X-RAY DIFFRACTION (2.4 Å)