6G9P
Structural basis for the inhibition of E. coli PBP2
Summary for 6G9P
Entry DOI | 10.2210/pdb6g9p/pdb |
Related | 6G9F |
Descriptor | Peptidoglycan D,D-transpeptidase MrdA (2 entities in total) |
Functional Keywords | penicillin binding protein, hydrolase-antibiotic complex, hydrolase/antibiotic |
Biological source | Escherichia coli K-12 |
Total number of polymer chains | 1 |
Total formula weight | 65075.52 |
Authors | |
Primary citation | Levy, N.,Bruneau, J.M.,Le Rouzic, E.,Bonnard, D.,Le Strat, F.,Caravano, A.,Chevreuil, F.,Barbion, J.,Chasset, S.,Ledoussal, B.,Moreau, F.,Ruff, M. Structural Basis for E. coli Penicillin Binding Protein (PBP) 2 Inhibition, a Platform for Drug Design. J.Med.Chem., 62:4742-4754, 2019 Cited by PubMed: 30995398DOI: 10.1021/acs.jmedchem.9b00338 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.101 Å) |
Structure validation
Download full validation report