6G8D

Crystal Structure of the Amyloid-like LNIYQY segment from the R1 repeat of the E. coli Biofilm-associated CsgA Curli protein

6G8D の概要

• エントリーDOI: 10.2210/pdb6g8d/pdb
• 分子名称: Major curlin subunit (2 entities in total)
• 機能のキーワード: bacterial steric-zipper cross-beta amyloid fibril from e. coli, protein fibril
• 由来する生物種: Escherichia coli K-12
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 812.91

構造登録者

Landau, M.,Perov, S. (登録日: 2018-04-08, 公開日: 2019-04-24, 最終更新日: 2019-10-23)

• 主引用文献: Perov, S.,Lidor, O.,Salinas, N.,Golan, N.,Tayeb-Fligelman, E.,Deshmukh, M.,Willbold, D.,Landau, M.; Structural Insights into Curli CsgA Cross-beta Fibril Architecture Inspire Repurposing of Anti-amyloid Compounds as Anti-biofilm Agents.; Plos Pathog., 15:e1007978-e1007978, 2019; PubMed: 31469892; DOI: 10.1371/journal.ppat.1007978

実験手法

X-RAY DIFFRACTION (1.85 Å)