6G74

Structure of the Y21F variant of quinolinate synthase in complex with phthalate

Summary for 6G74

• Entry DOI: 10.2210/pdb6g74/pdb
• Related: 6F48 6F4D 6F4L
• Descriptor: Quinolinate synthase A, IRON/SULFUR CLUSTER, PHTHALIC ACID, ... (4 entities in total)
• Functional Keywords: nad biosynthesis, iron sulfur cluster, transferase
• Biological source: Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
• Cellular location: Cytoplasm : Q9X1X7
• Total number of polymer chains: 2
• Total formula weight: 70054.35

Authors

Volbeda, A.,Fontecilla-Camps, J.C. (deposition date: 2018-04-04, release date: 2018-04-25, Last modification date: 2024-01-17)

• Primary citation: Volbeda, A.,Saez Cabodevilla, J.,Darnault, C.,Gigarel, O.,Han, T.H.,Renoux, O.,Hamelin, O.,Ollagnier-de-Choudens, S.,Amara, P.,Fontecilla-Camps, J.C.; Crystallographic Trapping of Reaction Intermediates in Quinolinic Acid Synthesis by NadA.; ACS Chem. Biol., 13:1209-1217, 2018; PubMed: 29641168; DOI: 10.1021/acschembio.7b01104

Experimental method

X-RAY DIFFRACTION (2 Å)