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6G6Z

Eg5-inhibitor complex

Summary for 6G6Z
Entry DOI10.2210/pdb6g6z/pdb
DescriptorKinesin-like protein KIF11, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total)
Functional Keywordseg5, kif11, eg5-inhibitor, cell cycle
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight41938.59
Authors
Talapatra, S.K.,Kozielski, F.,Tham, C.L. (deposition date: 2018-04-04, release date: 2018-08-08, Last modification date: 2024-01-17)
Primary citationTalapatra, S.K.,Tham, C.L.,Guglielmi, P.,Cirilli, R.,Chandrasekaran, B.,Karpoormath, R.,Carradori, S.,Kozielski, F.
Crystal structure of the Eg5 - K858 complex and implications for structure-based design of thiadiazole-containing inhibitors.
Eur J Med Chem, 156:641-651, 2018
Cited by
PubMed: 30031975
DOI: 10.1016/j.ejmech.2018.07.006
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

217157

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