6G0E

BRD4 (BD1) in complex with APSC-derived ligands

Summary for 6G0E

• Entry DOI: 10.2210/pdb6g0e/pdb
• Descriptor: Bromodomain-containing protein 4, 4-[2-(4-cyclohexylpiperazin-4-ium-1-yl)-2-oxidanylidene-ethyl]sulfanyl-1-ethyl-quinolin-2-one, FORMIC ACID, ... (6 entities in total)
• Functional Keywords: brd4, transcription
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 15744.09

Authors

Pretzel, J.,Humbeck, L. (deposition date: 2018-03-18, release date: 2020-01-08, Last modification date: 2024-01-17)

• Primary citation: Humbeck, L.,Pretzel, J.,Spitzer, S.,Koch, O.; Discovery of an Unexpected Similarity in Ligand Binding Between BRD4 and PPARgamma; Chemrxiv, 2019; DOI: 10.26434/chemrxiv.11472618

Experimental method

X-RAY DIFFRACTION (1.613 Å)