6G0E
BRD4 (BD1) in complex with APSC-derived ligands
Summary for 6G0E
Entry DOI | 10.2210/pdb6g0e/pdb |
Descriptor | Bromodomain-containing protein 4, 4-[2-(4-cyclohexylpiperazin-4-ium-1-yl)-2-oxidanylidene-ethyl]sulfanyl-1-ethyl-quinolin-2-one, FORMIC ACID, ... (6 entities in total) |
Functional Keywords | brd4, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 15744.09 |
Authors | Pretzel, J.,Humbeck, L. (deposition date: 2018-03-18, release date: 2020-01-08, Last modification date: 2024-01-17) |
Primary citation | Humbeck, L.,Pretzel, J.,Spitzer, S.,Koch, O. Discovery of an Unexpected Similarity in Ligand Binding Between BRD4 and PPARgamma Chemrxiv, 2019 Cited by DOI: 10.26434/chemrxiv.11472618PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.613 Å) |
Structure validation
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