6FZI

Crystal Structure of a Clostridial Dehydrogenase at 2.55 Angstroems Resolution

6FZI の概要

• エントリーDOI: 10.2210/pdb6fzi/pdb
• 分子名称: Glyceraldehyde-3-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, GLYCEROL, ... (6 entities in total)
• 機能のキーワード: clostridium perfringens, gapdh, nad, dehydrogenase, oxidoreductase, anacardic acid, curcumin, complement, c5a, c3a, c3
• 由来する生物種: Clostridium perfringens SM101
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 146011.21

構造登録者

Gomez, S.,Querol-Garcia, J.,Sanchez-Barron, G.,Subias, M.,Gonzalez-Alsina, A.,Melchor-Tafur, C.,Franco-Hidalgo, V.,Alberti, S.,Rodriguez de Cordoba, S.,Fernandez, F.J.,Vega, M.C. (登録日: 2018-03-14, 公開日: 2019-03-27, 最終更新日: 2024-01-17)

• 主引用文献: Gomez, S.,Querol-Garcia, J.,Sanchez-Barron, G.,Subias, M.,Gonzalez-Alsina, A.,Franco-Hidalgo, V.,Alberti, S.,Rodriguez de Cordoba, S.,Fernandez, F.J.,Vega, M.C.; The Antimicrobials Anacardic Acid and Curcumin Are Not-Competitive Inhibitors of Gram-Positive Bacterial Pathogenic Glyceraldehyde-3-Phosphate Dehydrogenase by a Mechanism Unrelated to Human C5a Anaphylatoxin Binding.; Front Microbiol, 10:326-326, 2019; PubMed: 30863383; DOI: 10.3389/fmicb.2019.00326

実験手法

X-RAY DIFFRACTION (2.55 Å)