6FVQ

The active form of a pentameric ion channel (sTeLIC) gated by alkaline pH - R86A

Summary for 6FVQ

Entry DOI	10.2210/pdb6fvq/pdb
Descriptor	Cys-loop ligand-gated ion channel, TETRAETHYLENE GLYCOL, nonyl beta-D-glucopyranoside (3 entities in total)
Functional Keywords	pentameric ligand-gated ion channel., membrane protein
Biological source	endosymbiont of Tevnia jerichonana (vent Tica)
Total number of polymer chains	5
Total formula weight	188626.64
Authors	Hu, H.,Delarue, M. (deposition date: 2018-03-05, release date: 2018-05-16, Last modification date: 2024-05-08)
Primary citation	Hu, H.,Nemecz, A.,Van Renterghem, C.,Fourati, Z.,Sauguet, L.,Corringer, P.J.,Delarue, M. Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation. Proc. Natl. Acad. Sci. U.S.A., 115:E3959-E3968, 2018 Cited by PubMed: 29632192 DOI: 10.1073/pnas.1717700115 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.3 Å)

Structure validation