6FS7

Influenza A/California/04/2009 (pH1N1) endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA)

Summary for 6FS7

Entry DOI	10.2210/pdb6fs7/pdb
Descriptor	Polymerase acidic protein,Polymerase acidic protein, MANGANESE (II) ION, Baloxavir acid, ... (4 entities in total)
Functional Keywords	influenza, endonuclease, inhibitor, viral protein
Biological source	Influenza A virus (A/California/04/2009(H1N1)) More
Total number of polymer chains	6
Total formula weight	138642.16
Authors	Cusack, S.,Speranzini, V. (deposition date: 2018-02-19, release date: 2018-07-11, Last modification date: 2024-01-17)
Primary citation	Omoto, S.,Speranzini, V.,Hashimoto, T.,Noshi, T.,Yamaguchi, H.,Kawai, M.,Kawaguchi, K.,Uehara, T.,Shishido, T.,Naito, A.,Cusack, S. Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil. Sci Rep, 8:9633-9633, 2018 Cited by PubMed: 29941893 DOI: 10.1038/s41598-018-27890-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.96 Å)

Structure validation