6FO1
Human R2TP subcomplex containing 1 RUVBL1-RUVBL2 hexamer bound to 1 RBD domain from RPAP3.
Summary for 6FO1
Entry DOI | 10.2210/pdb6fo1/pdb |
EMDB information | 4287 |
Descriptor | RuvB-like 1, RuvB-like 2, RNA polymerase II-associated protein 3, ... (4 entities in total) |
Functional Keywords | r2tp, hsp90 co-chaperone, pih1d1, rpap3, ruvbl1-ruvbl2, chaperone |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 7 |
Total formula weight | 382951.89 |
Authors | Martino, F.,Munoz-Hernandez, H.,Rodriguez, C.F.,Pearl, L.H.,Llorca, O. (deposition date: 2018-02-05, release date: 2018-04-04, Last modification date: 2019-12-11) |
Primary citation | Martino, F.,Pal, M.,Munoz-Hernandez, H.,Rodriguez, C.F.,Nunez-Ramirez, R.,Gil-Carton, D.,Degliesposti, G.,Skehel, J.M.,Roe, S.M.,Prodromou, C.,Pearl, L.H.,Llorca, O. RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex. Nat Commun, 9:1501-1501, 2018 Cited by PubMed: 29662061DOI: 10.1038/s41467-018-03942-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.57 Å) |
Structure validation
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