6FNQ

Ergothioneine-biosynthetic methyltransferase EgtD in complex with N,N,N-trimethylhistidine (hercynine)

6FNQ の概要

• エントリーDOI: 10.2210/pdb6fnq/pdb
• 分子名称: Histidine N-alpha-methyltransferase, N,N,N-trimethyl-histidine, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: ergothioneine, methyltransferase, product complex, transferase
• 由来する生物種: Mycobacterium smegmatis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 71538.74

構造登録者

Vit, A.,Blankenfeldt, W.,Seebeck, F.P. (登録日: 2018-02-05, 公開日: 2018-06-13, 最終更新日: 2024-01-17)

• 主引用文献: Misson, L.,Burn, R.,Vit, A.,Hildesheim, J.,Beliaeva, M.A.,Blankenfeldt, W.,Seebeck, F.P.; Inhibition and Regulation of the Ergothioneine Biosynthetic Methyltransferase EgtD.; ACS Chem. Biol., 13:1333-1342, 2018; PubMed: 29658702; DOI: 10.1021/acschembio.8b00127

実験手法

X-RAY DIFFRACTION (1.75 Å)