6FNA

Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins

6FNA の概要

• エントリーDOI: 10.2210/pdb6fna/pdb
• 分子名称: 14-3-3 protein zeta/delta, [2-[2-oxidanylidene-2-[[3-[2-[2-[2-[3-oxidanylidene-3-[2-[3-[2-[2-[2-[[4-[2-(2-phosphonophenoxy)ethanoylamino]phenyl]carbonylamino]ethoxy]ethoxy]ethoxy]propanoylamino]ethylamino]propoxy]ethoxy]ethoxy]ethylcarbamoyl]phenyl]amino]ethoxy]phenyl]phosphonic acid, BENZOIC ACID, ... (7 entities in total)
• 機能のキーワード: inhibition, mono- and bivalent 14-3-3 inhibitors, supramolecular lysine-peg, protein binding
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55550.00

構造登録者

Bier, D.,Ottmann, C. (登録日: 2018-02-02, 公開日: 2018-07-04, 最終更新日: 2024-01-17)

• 主引用文献: Yilmaz, E.,Bier, D.,Guillory, X.,Briels, J.,Ruiz-Blanco, Y.B.,Sanchez-Garcia, E.,Ottmann, C.,Kaiser, M.; Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins.; Chemistry, 24:13807-13814, 2018; PubMed: 29924885; DOI: 10.1002/chem.201801074

実験手法

X-RAY DIFFRACTION (2.12 Å)